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pentobarbital will reduce the extent or effect of diazepam buccal by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of. Sturdy or reasonable CYP3A4 inducers may perhaps increase charge of diazepam elimination; for that reason, efficacy of diazepam may be reduced.fentanyl transmucosal and pentobarbital both raise sedat